Publication:

運動後補充葡萄糖對餐後血脂代謝之影響

過去研究中指出餐前單次的耐力運動可以降低餐後血脂升高的現象，然而運動造成的能量的負平衡是否會影響餐後血脂肪清除率目前仍然不清楚。本研究以低強度走路運動並以葡萄糖填補運動時所消耗的熱量，探討能量回補與運動降低餐後血脂之影響。方法：以9名沒運動習慣的健康成年男性(受測者年齡為23.8±0.2歲，身高為172.8±1.9公分，體重為69.8±1.5公斤，最大攝氧量為49.0±3.8ml/kg/min，運動坡度6.0±0.1%，葡萄糖補充量為128.8±11.2公克，能量消耗為515.2±45.0 kcal)。隨機進行三組實驗：控制組(CON)、運動組(EX)、運動加葡萄糖補充組(EXG)。EX及EXG組在實驗前一天下午進行1小時50%最大攝氧量的走路運動，其中EXG組在運動後以葡萄糖補充因運動所消耗的能量，CON組則完全休息，三組均在隔天早上給予高脂肪餐，收集並分析餐前、餐後30分鐘、1、2、3、4、5、6小時的血液樣本。實驗數據以雙因子變異數分析(repeat measure two-way ANOVA)進行統計分析。結果：在本研究的結果中，發現EXG組和EX組皆能顯著減少餐後的血脂肪濃度，而血漿中TG濃度-時間增加的曲線下面積來說，有運動的兩組皆能顯著減少餐後血脂肪的增加量。結論：本研究顯示在運動能加速餐後血脂肪的清除率，但是中低強度下運動後能量的平衡與否並不會影響高脂肪餐後的血脂肪清除率。

Previous studies showed that a single bout of endurance exercise effectively to reduce postprandial lipemia. However, the magnitude of reducing postprandial lipemia via exercise induced energy negative balance is still unclear. The present study was to investigate effect of the brisk walking with energy replacement by glucose on rate of postprandial lipid clearance. Methods: Nine healthy and inactive young males (age 23.8±0.2 years; height 172.8±1.9 cm; weight 69.8±1.5 kg; VO2max 49.0±3.8ml/kg/min; slope of exercise 6.0±0.1%，glucose replacement 128.8±11.2 g; energy expended 515.2±45.0 kcal) completed 3 experimental trials: control trial (CON), the exercise trial (EX), exercise with glucose supplementation trial (EXG). During EX and EXG trials, subjects exercised at 50% VO2max for an hour in the afternoon on the day before the experiment while the CON trial were rest. In EXG trial, a glucose supplementation, which the energy equal to the energy expenditure during exercise, were given to the subjects after exercise. An oral fat tolerance test meal was given to subjects in the next morning after an overnight fast. Blood samples were collected at fasting, 30min, 1, 2, 3, 4, 5, 6 h during postprandial period. Data were analyzed by using the repeat measure of two-way ANOVA for statistical analysis. Results: the results showed that the plasma triglyceride (TG) concentrations of the EXG and EX trials were significantly lower than the CON trial during postprandial state. Conclusion: The present study showed that exercise may increase the clearance of postprandial plasma TG independently, regardless energy balance.