張振崗Chang, Chen-Kang2017-02-222025-07-302017-02-222017-02-22https://ir.ntus.edu.tw/handle/987654321/70579學位類別：碩士校院名稱：國立台灣體育學院系所名稱：競技運動學系碩士班學號：19304009畢業學年度：94年論文頁數：74頁　　餐後高三酸甘油酯症(postprandial hypertriglyceridemia)是心血管疾病的危險因子之一，低升糖指數(low glycemic index, LGI)飲食可幫助健康者或高血脂症、糖尿病病患及心血管疾病患者降低脂質、血糖、insulin濃度。運動前食用LGI食物，運動中的脂肪氧化率較高升糖指數(high glycemic index, HGI)食物為高。本研究目的為探討3天不同升糖指數的飲食介入和3天的運動介入對餐後脂質代謝的影響。以無規律運動健康男性6名為受試者，採用交叉實驗設計，受試者須完成4種處置，分別為LGI組、HGI組、LGI+運動(LGI+EX)組、HGI+運動(HGI+EX)組，LGI食物GI估計值為40，HGI食物GI估計值為80，運動強度為50%VO2max快走60分鐘。在第4天進行口服脂肪耐受力測試(1.2 g脂肪，1.1 g碳水化合物，0.33 g蛋白質/kg body mass)，於第0、30、60、120、180、240、300、360分鐘收集血液樣本，分析血漿中glucose、總膽固醇(total cholesterol, TC)、低密度脂蛋白(low density lipoprotein cholesterol, LDL-C)、高密度脂蛋白(high density lipoprotein cholesterol, HDL-C)、三酸甘油酯(triglyceride, TG)。TG濃度具有處置與時間效應，在相同時間點不同處置方面，TG濃度於0分鐘、30分鐘時，HGI+EX組顯著低於LGI組，TG曲線下面積HGI+EX組顯著低於LGI+EX組。TC濃度具有處置與時間效應，在相同時間點不同處置間，0分鐘HGI與HGI+EX組顯著低於LGI組，30、180、240分鐘HGI+EX組顯著低於LGI組，120分鐘HGI組顯著低於LGI組。在HDL-C濃度方面則只有時間效應。LDL-C濃度具有顯著處置與時間交互作用效應，在相同時間不同處置間，0分鐘HGI組與HGI+EX組顯著低於LGI組，30分鐘與60分鐘HGI+EX組顯著低於LGI組。glucose曲線下面積HGI組顯著低於其他三組。insulin曲線下面積LGI+EX組顯著低於其他三組。研究結果顯示，運動增強了不同GI食物對OFTT後TG濃度的影響，只單獨改變食物的GI，對餐後TG增加幅度並無顯著影響，但加上運動後，便顯著降低OFTT後TG濃度。　　Postprandial hypertriglyceridemia is one of the risk factors for cardiovascular disease. It has been shown that low glycemic index (LGI) diet can help reduce plasma levels of lipid, glucose, and insulin in healthy people or patients with hyperlipidemia, diabetes, and cardiovascular disease. Consuming LGI diet before exercise resulted in higher fat oxidation than HGI diet. However, little is known regarding the effect of diets with different and exercise on postprandial lipid metabolism. The purpose of this study was to exam the effect of diets with different GI and exercise for 3 days on postprandial lipid metabolism. The subjects were 6 healthy males without regular exercise. A cross-over experimental design was used. All subjects performed 4 different treatments, including LGI, high glycemic index (HGI), LGI diet and exercise (LGI+EX), and HGI diet and exercise (HGI+EX). The estimated GI value for LGI and HGI diets were 40 and 80, respectively. The exercise protocol was brisk walking at 50% VO2max for 60 min. On the fourth day oral fat tolerance test (1.2g fat, 1.1g carbohydrate, 0.33g protein / kg body mass) was performed. Blood samples were collected in 0, 30, 60, 120, 180, 240, and 300 min after consuming the test meal. Plasma levels of glucose, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and triglyceride (TG) were analyzed. TG concentration showed treatment and time effects. TG concentrations were significantly lower in HGI+EX group at 0 and 30 min than those in LGI group. TG concentrations HGI+EX group had lower TG incremental area under the curve (IAUC) than LGI+EX group. TC concentration showed treatment and time effects. HGI and HGI+EX groups showed lower TC levels than LGI group at 0 min, while HGI+EX group was lower than LGI group at 30, 180, and 240 min. HGI group had lower TC level than LGI group at 120 min. There was only time effect in HDL-C concentration. LDL-C concentration showed an interaction effect of treatment and time. LDL-C levels were lower in HGI and HGI+EX groups than LGI group at 0 min, while lower in HGI+EX groups than LGI groups at 30 and 60 min. Glucose IAUC was the lowest in HGI group, while insulin IAUC was the lowest in LGI+EX group, compared to other 3 groups. The results of this study suggested that exercise may reinforce the effect of diets with different GI values on postprandial lipid metabolism. Diet along did not affect the changes in TG concentrations after a test meal. However, the 2 exercise groups showed lower postprandial TG levels compared to the non-exercise groups.第壹章　緒論……………………………………………………01 　一、研究背景…………………………………………………01 　二、研究目的…………………………………………………01 第貳章　文獻回顧………………………………………………03 　一、餐後脂質代謝與心血管疾病……………………………03 　二、運動與餐後脂質代謝……………………………………04 　三、運動降低餐後TG的機轉…………………………………08 　四、不同G I飲食對餐後脂質代謝的影響……………………11 第參章　研究方法………………………………………………14 　一、實驗對象…………………………………………………14 　二、實驗設計…………………………………………………14 　三、飲食控制…………………………………………………14 　四、運動介入…………………………………………………15 　五、OFTT與血液分析…………………………………………15 　六、統計分析…………………………………………………19 第肆章　結果……………………………………………………20 　一、受試者基本資料…………………………………………20 　二、血液生化值………………………………………………20 第伍章　討論……………………………………………………22 參考文獻…………………………………………………………43398331 bytesapplication/pdf升糖指數;三酸甘油酯;餐後脂肪代謝;口服脂肪耐受度測試glycemic index;triglyceride;postprandial lipid metabolism;oral fattolerance testthesis