巫錦霖;張振崗Wu, Ching-Lin;Chang, Chen-Kang2017-02-222025-07-302017-02-222017-02-22https://ir.ntus.edu.tw/handle/987654321/70879學位類別：碩士校院名稱：國立台灣體育大學系所名稱：運動健康科學系碩士班學號：19606005畢業學年度：97年論文頁數：49頁　　彽氧環境下運動視為對身體的壓力來源，進而對身體的免疫系統產生影響。補充支鏈胺基酸(branched chain amino acid ,BCAA)與碳水化合物(carbohydrate)不僅被認為對於運動表現有所影響，也可能會影響免疫反應。七名平時有運動習慣的健康成年男性，年齡25.5±0.6歲，身高168.4±1.8cm，體重69.86±2.8kg，最大攝氧量38.2±1.8ml．min-1．kg-1，隨機重覆四次實驗，分為BCAA組(攝取BCAA 12g)、CHO (攝取75g/250ml)組、BCAA+CHO (12g+75g/250ml)組、PLA(250ml)組，在低氧環境下(15% O2)休息60分鐘後，開始50%VO2max的強度90分鐘的腳踏車運動，再以85%VO2max的強度直至衰竭，休息兩個小時。分析血液中介白素-6(IL-6)，白血球(white blood cell)、淋巴球(lymphocyte)、噬中性白血球(neturophil)，可體醇(cortisol)、胰島素(insulin)，血糖(glucose)之改變。IL-6、TNF-α的濃度並無顯著改變，淋巴球在運動後BCAA+glucose組與glucose組顯著高於BCAA組(p=0.019,0.011)。本研究顯示，短期的低氧運動刺激對於血液中細胞激素並無顯著的影響，在身體周邊的免疫相關的血球數量是有增加。　　Ingestion of carbohydrate (CHO) and branched-chain amino acids (BCAAs) before exercise might improve exercise performance. However the effects on exercise induced immune stress in hypoxia environment are still unclear. We recruited 7 health adult male( age: 25.5 ± 0.6 yrs, height: 168.4±1.8cm, weight: 69.86±2.8kg, VO2max: 38.2±1.8ml．min-1．kg-1) to participate in this study. 　　All subjects completed 4 experimental trials, BCAA (ingesting BCAAs 12g/250ml), CHO (ingesting glucose 75g/250ml), BCAA+CHO (ingesting BCAA+glucose 12g+ 75g/250ml), PLA(placebo 250ml) in a randomized order. After overnight fasting, subject were asked to ingested the test drinks and rest in the hypoxia chamber ( O2 15% ) for 60 mins before undertaking the exercise. Subjects exercised at 50%VO2 max for 90mins on a cycle ergometer, then the intensity increased to 85% VO2 max until volitional fatigue. After exercise, subjects were asked to rest for 2 hours in the hypoxia champer. Blood samples and saliva samples were collected before exercise, at 30min intervals during exercise, at fatigue, and every hour during post-exercise. Plasma samples were analyzed for IL-6 , TNF-α , cortisol, insulin, and glucose concentrations. White blood cell, lymphocyte, neturophil numbers were also measured. The results showed that there were no significant changes in plasma cytokines and saliva IgA during 4 trials. White blood cell, lymphocyte, and neturophil numbers were increased following exercise. The current results suggested ingesting CHO and BCAAs before exercise in acute hypoxia environment did not change cytokine secretion. However, the peripheral white blood cell were increased.目　次 第壹章　緒論……………………………………………………………1 　第一節　研究背景……………………………………………………1 　第二節　研究目的……………………………………………………2 　第三節　研究假設……………………………………………………3 　第四節　名詞解釋……………………………………………………3 　第五節　研究限制……………………………………………………3 第貳章　文獻探討………………………………………………………5 　第一節　低氧環境下運動對於身體細胞激素的影響………………5 　第二節　低氧環境下耐力運動與碳水化合物補充之影響…………11 　第三節　低氧環境下耐力運動前攝取BCAA對於細胞激素的影響…14 　第四節　總結…………………………………………………………15 第叁章　實驗步驟與研究方法…………………………………………17 　第一節　實驗對象……………………………………………………17 　第二節　實驗設計與流程……………………………………………17 　第三節　分析方法……………………………………………………22 　第四節　統計方法……………………………………………………22 第肆章　結果……………………………………………………………23 　第一節　受試者基本資料……………………………………………23 　第二節　攝取不同補充劑對於血液中生化值的影響………………23 　第三節　攝取不同補充劑對於唾液中免疫球蛋白的影響…………25 第伍章　討論……………………………………………………………26 引用文獻…………………………………………………………………29 　中文文獻………………………………………………………………29 　英文文獻………………………………………………………………29369293 bytesapplication/pdf低氧;支鏈胺基酸;細胞激素hypoxia;BCAAs;cytokinethesis