Publication:

運動後酒精對健康之影響

中文摘要

本研究之目的在於探討運動後飲酒對人體健康之影響。實驗以二十四名自願參與者(平均年齡23.7±2.2歲、身高169.1±3.7公分、體重57.2±4.4公斤)，隨機分為三組，每組八名，於衰竭運動後分別飲用紅酒、米酒頭及開水，再分別採集運動前後與飲酒後之血液樣本進行生化分析，項目分析包括一、血液抗氧化指標：超氧化物歧化酶﹙superoxide dismutase；SOD﹚、麩胱甘月太過氧化酶(glutathione peroxides；GPx)。二、過氧化傷害指標：脂質過氧化物丙二醛(malondialdehyde；MDA)。三、骨骼肌破損指標：乳酸去氫酶(lactate dehydrogenase；LDH)及肌酸激酶(creatine kinase；CK)。四、心肌破損指標MB型肌酸激酶(creatine kinase polypeptide subunit MB；CK-MB)。五、肝細胞破損指標：谷丙轉氨酶(glutamic-pyruvic transaminase ; GPT)、谷草轉氨酶(glutamic oxaloacet transaminase ; GOT)。檢測數值以雙因子重複量數分析後發現，運動後飲用紅酒之CK-MB顯著低於米酒頭組(p<.05)，其餘各生化值則未出現顯著之差異。

本研究獲得以下結論：運動後飲用適量紅酒對心肌細胞之破損具有保護作用，運動後飲用後飲用米酒頭則造成心肌細胞破損之加成作用。

Abstract

The purpose of this study was to investigate the effects of alcohol intake on health after exercise. Twenty-four volunteers (age=23.7±2.2yrs, height=169.0±3.7cm, weight=57.5±4.4kg) were randomly divided into red wine (n=8), Mizhiu Tou (n=8), and water groups (n=8). Volunteers drank red wine、Mizhiu Tou and water after exhaustion exercise. Blood samples were taken before exercise(BE)、after exercise (AE) and alcohol intake after exercise (AAE)for biological analysis.

We measured 1) the indicators of body antioxidant and peroxidation such as superoxide dismutase (SOD), glutathione peroxidase (GPx) and the lipid peroxidation as malondialdehyde (MDA), 2) the indicators of muscular damage such as creatinine kinase (CK) and lactate dehydrogenase (LDH), 3) the indicators of myocardium damage such as creatine kinease polypeptide subunit MB (CK-MB), 4) the indicator of liver damage such as glutamic-oxoloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT). The value was analyzed by Two-way MANOVA.

The results showed that after exhaustion exercise CK-MB-AAE of red wine intake group was lower significantly than Mizhiu Tou groups (p<0.05).The conclusions of this study are:

1.After exhausted exercise, red wine intake has the protective.effect of the myocardium.

2.After exhausted exercise, Mizhiu Tou intake cause more serious..damage .of myocardium.