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Effects of Resistance Exercise on Glycated Hemoglobin and Functional Performance in Older Patients with Comorbid Diabetes Mellitus and Knee Osteoarthritis: A Randomized Trial

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cris.lastimport.scopus2026-02-28T16:01:40Z
dc.creatorChen, Shu-Mei
dc.creatorShen, Feng-Chih
dc.creatorChen, Jung-Fu
dc.creatorChang, Wen-Dien
dc.creatorChang, Nai-Jen
dc.date2020-01
dc.date.accessioned2021-11-03T03:00:19Z
dc.date.accessioned2025-07-27T15:02:54Z
dc.date.available2021-11-03T03:00:19Z
dc.date.issued2021-11-03T03:00:19Z
dc.description.abstractType 2 diabetes mellitus (T2DM) is significantly associated with osteoarthritis (OA). This study investigated the effects of two resistance exercise approaches on glycated hemoglobin (HbA1c) level and function performance. Enrolled were 70 older patients with both T2DM and knee OA. The dynamic group performed resistance exercises with an elastic resistance band. The isometric group underwent isometric contraction exercises. After the 12-week intervention, a significant within-group improvement (all p < 0.001) was observed for the chair stand test (CST; 10.8%, vs. 7.1%), timed up and go (TUG) test (12.6% vs. 7.6%), Western Ontario and McMaster Universities Osteoarthritis (WOMAC) physical function subscale (62.3% vs. 36.1%), and overall WOMAC (54.5% vs. 34.5%) in the dynamic and isometric group, respectively. In addition, in terms of between-group differences, the dynamic group had significant improvements in CST (p = 0.011), TUG (p < 0.001), WOMAC physical function subscale (p = 0.033), and overall WOMAC (p = 0.036) scores compared with the isometric group. However, no significant change in HbA1c was observed in either group. In conclusion, the dynamic resistance exercise significantly improved muscle strength, dynamic balance, and physical function in this comorbid population; however, there was no notable difference in change in HbA1c among different resistance exercises.
dc.format.extent103 bytes
dc.format.mimetypetext/html
dc.identifier.doi10.3390/ijerph17010224
dc.identifier.issn1661-7827
dc.identifier.urihttps://ir.ntus.edu.tw/handle/987654321/64444
dc.languageen_US
dc.publisherBASEL, SWITZERLAND: MDPI
dc.relationINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 17(1)
dc.subjecttherapeutic exercise
dc.subjectphysical activity
dc.subjectdiabetes
dc.subjectperformance
dc.subjectosteoarthritis
dc.titleEffects of Resistance Exercise on Glycated Hemoglobin and Functional Performance in Older Patients with Comorbid Diabetes Mellitus and Knee Osteoarthritis: A Randomized Trial
dc.typearticle
dspace.entity.typePublication

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