Publication: New Abietane-type Diterpenoids from the Bark of Cryptomeria japonica
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Date
2019-11-15T02:47:49Z
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SAGE
Abstract
Two new abietane-type diterpenoids, 15-hydroxy-12-O-methylsugiol (1) and 2a-hydroxy-12-O-methylsugiol (2) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were elucidated on the basis of spectroscopic analysis and comparison of NMR data with those of known analogues. Compounds 2 showed 13.5% inhibition towards xanthine oxidase enzyme at the concentration of 75 μM
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Keywords
Cupressaceae; Cryptomeria japonica; Abietane; Diterpenoid; Traditional Herbal Medicine