補充碳水化合物可能會藉由增加外源性碳水化合物氧化率等好處使得耐力運動表現提升，而補充支鏈胺基酸可能會在長時間運動後期藉由延緩中樞神經疲勞，增加運動表現，不過研究大多都在常氧下進行，在急性低氧刺激使得代謝上發生改變後可能會有不同的結果。因此本研究目的為探討急性低氧環境下補充碳水化合物以及支鏈胺基酸，對於耐力運動表現以及其生理指標的影響。以七名平時有運動習慣，但是沒接受正式訓練的健康男性大學生為研究對象，分成補充12克的支鏈胺基酸、12克的支鏈胺基酸加上75克的葡萄糖、75克的葡萄糖以及安慰劑等四組，在急性低氧環境下的運動前一小時補充。隨後進行90分鐘50%最大攝氧量的腳踏車運動，之後緊接著進行85%最大攝氧量的運動表現測試直到衰竭，並在整個實驗期間採集血液樣本。結果顯示四組的運動表現並沒有顯著的差異（運動表現測試：BCAA組353.4±84.2秒；BCAA+GLU組340.9±90秒；GLU組407±77.3秒；安慰劑組291.6±42.9秒）。血漿中胰島素的濃度為BCAA+GLU組顯著大於BCAA組(p=0.008)以及安慰劑組(p=0.004)。游離脂肪酸濃度則是BCAA組顯著大於葡萄糖組(p=0.012)。血糖濃度BCAA+GLU組顯著大於BCAA組(p=0.02)。血漿中氨的濃度，以及運動期間脂肪氧化率以及碳水化合物氧化率四組間也是沒有顯著的差異。研究結果顯示，在急性低氧下補充碳水化合物以及支鏈胺基酸，對於運動表現並沒有顯著的影響。

　　Carbohydrate supplementation may improve endurance performance through increasing exogenous carbohydrate oxidation during exercise. Similarly, branched-chain amino acids (BCAAs) supplementation may delay the central nervous from being fatigue at the end of exercise, and improve endurance exercise performance. Since the previous studies were performed at sea level, there may have a different result on physiological and metabolism response for acute hypoxia environment. The purpose of this study was to determine whether carbohydrate and BCAAs supplementation could alter exercise performance and physiological response in an acute hypoxia condition. Seven healthy college male subjects completed 4 experimental trials. They ingested either 12 g of BCAAs (BCAA group), 、12g Branched-chain amino acids plus 75g glucose (BCAA+GLU group)、 75g glucose (GLU group) and placebo (PLA group) 1 hour before exercise in acute hypoxia, respectively. Subjects exercised at 50% VO2 max on cycle erogmeter for 90 minutes, and then increased the intensity to 85% VO2 max exercised to exhaustion. The result shown that there were no difference on exercise performance between 4 trials (85% VO2 max to fatigue: BCAA trial 353.4±84.2 seconds, BCAA+GLU 340.9±90 seconds, GLU 407±77.3 seconds, PLA 291.6±42.9). Blood insulin concentrations were significant higher in BCAA+GLU compared to BCAA (p=0.008) and PLA (p=0.004). NEFA concentrations were significant higher in BCAA than that of GLU (p=0.012). Blood glucose concentrations were significant higher in BCAA+GLU than that of BCAA (p=0.02). There were no differences in plasma NH3 concentration、fat oxidation rates and carbohydrate oxidation rates during exercise between 4 trials. The current results suggested ingestion carbohydrate and BCAAs did not alter endurance performance in acute hypoxia environment.